Comparison

anti- BARD1 antibody

Manufacturer FineTest
Category
Type Antibody Monoclonal
Specific against Human
Isotype IgG
Format liquid
Amount 100ug
Host Rabbit
Item no. FNab00803-100ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Clonality
polyclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
Immunogen
BRCA1 associated RING domain 1
Observed MW
90-100 kDa
Uniprot ID
Q99728
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500-1:1000
Gene ID
580
Research Area
Epigenetics, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
available

Delivery expected until 4/25/2024 

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