Item no. |
FNab00922-100ug |
Manufacturer |
FineTest
|
Amount |
100ug |
Category |
|
Type |
Antibody Monoclonal |
Format |
liquid |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
10q23del, Activin receptor like kinase 3, ACVRLK3, ALK 3, ALK3, BMP type 1A receptor, BMPR 1A, BMPR1A, CD292, SKR5 |
Available |
|
Purification |
Immunogen affinity purified |
Purity |
>=95% as determined by SDS-PAGE |
Clonality |
polyclonal |
Storage |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.) |
Background |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. |
Immunogen |
bone morphogenetic protein receptor, type IA |
Observed MW |
60 kDa |
Uniprot ID |
P36894 |
Tested Application |
ELISA, WB, IF, IP |
Recommended dilution |
WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100 |
Gene ID |
657 |
Research Area |
Stem Cells, Immunology, Cardiovascular |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.