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anti- BORIS antibody

anti- BORIS antibody

Manufacturer	FineTest
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human, Mouse
Clone	2B10
Isotype	IgG1
Format	liquid
Amount	100ug
Host	Mouse
Item no.	FNab00932-100ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Clonality	monoclonal
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
Immunogen	CCCTC-binding factor(zinc finger protein)-like
Observed MW	75 kDa
Uniprot ID	Q8NI51
Tested Application	ELISA, WB, IF
Recommended dilution	WB: 1:500-1:2000; IF: 1:10-1:100
Research Area	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 8/2/2023