Comparison

anti- BVES antibody

Manufacturer FineTest
Category
Type Antibody Monoclonal
Specific against Human, Mouse, Rat
Isotype IgG
Format liquid
Amount 100ug
Host Rabbit
Item no. FNab00992-100ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Clonality
polyclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
Immunogen
blood vessel epicardial substance
Observed MW
41-70 kDa
Uniprot ID
Q8NE79
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:100-1:1000; IHC: 1:20-1:200
Gene ID
11149
Research Area
Stem Cells, Developmental biology

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
available

Delivery expected until 4/25/2024 

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