Comparison

CAD antibody

Item no. FNab01183-100ug
Manufacturer FineTest
Amount 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Purity ≥95% as determined by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Multifunctional protein CAD,Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase,CAD
Available
Manufacturer - Targets
CAD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Clonality
polyclonal
Immunogen
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Observed MW
243 kDa
Purification
Immunogen affinity purified
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Manufacturer - Research Area
Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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