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PRKACB antibody

PRKACB antibody

Item no.	FNab06778-100ug
Manufacturer	FineTest
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta),PRKACB
Available
Manufacturer - Targets	PRKACB
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Clonality	polyclonal
Immunogen	protein kinase, cAMP-dependent, catalytic, beta
Observed MW	46-55 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Manufacturer - Research Area	Cell Division and Proliferation, Signal Transduction, Metabolism, Developmental biology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.