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TEX14 antibody

TEX14 antibody

Item no.	FNab08609-100ug
Manufacturer	FineTest
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Inactive serine/threonine-protein kinase TEX14,Protein kinase-like protein SgK307,Sugen kinase 307,Testis-expressed sequence 14,Testis-expressed sequence 14 protein,TEX14,SGK307
Available
Manufacturer - Targets	TEX14
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).
Clonality	polyclonal
Immunogen	testis expressed 14
Observed MW	180-200 kDa, 106 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Manufacturer - Research Area	Stem Cells

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