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Mouse monoclonal antibody to Human Cardiac Troponin I

Mouse monoclonal antibody to Human Cardiac Troponin I

Item no.	ICO-103-100
Manufacturer	Icosagen
Amount	100ug
Category	Antibodies Cell Biology Cell Status Necrosis Cytoskeleton Western Blot ELISA Primary Antibodies Microfilaments
Type	Antibody Monoclonal
Applications	ELISA, Western Blot
Clone	1D12
Specific against	other
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Background	Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle (Wikipedia)
Buffer	PBS pH 7.4; 0.1% NaN3
Clonality	Mouse monoclonal
Dissociation Constant (KD)	4.3 x 10-10 M
Immunogen	Human cardiac troponin I
Immunogen Description	Native, affinity purified human cardiac troponin I
Limitations	This product is for research use only
Protocol	ELISA, 0.05-0.1 ug/ml; WB, 0.2 to 0.5 ug/ml
Purification	Protein G purification
Storage	Store at –20…-70C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles
Uniprot ID	P19429

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/25/2025

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