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Chicken polyclonal antibody to human GFRa-1

Chicken polyclonal antibody to human GFRa-1

Item no.	ICO-303-100
Manufacturer	Icosagen
Amount	100ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	ELISA, Immunofluorescence, Western Blot
Specific against	other
Isotype	IgY
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	RET ligand 1, TGF-beta related neurotrophic factor receptor 1
Available
Background	Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)
Buffer	Concentrated ammonium sulphate in PBS pH 7.4
Clonality	Chicken polyclonal
Immunogen	human GFRa-1
Immunogen Description	Recombinant His-tagged human GFRa-1 protein produced using CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant
Limitations	This product is for research use only
Protocol	ELISA: 0.02 to 0.05 ug/ml; WB 0.1 to 0.2 ug/ml; IF 0.5 to 1 ug/ml Polyclonal antibody working titer has to be established practically for each particular antigen and assay format
Purification	GFRa-1 affinity purified
References	-
Storage	Store at +4 C upon receipt. As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
Uniprot ID	P56159

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/25/2025

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