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Mouse monoclonal antibody to human MANF (Mesencephalic astrocyte-derived neurotrophic factor)

Mouse monoclonal antibody to human MANF (Mesencephalic astrocyte-derived neurotrophic factor)

Item no.	ICO-311-100
Manufacturer	Icosagen
Amount	100ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	ELISA, Immunofluorescence, Western Blot
Clone	1G12
Specific against	other
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	ARMET, ARP
Available
Background	MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson’s disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta
Buffer	PBS pH 7.4, with 0.1% sodium azide
Clonality	Mouse monoclonal
Immunogen	Human MANF
Immunogen Description	Recombinant human MANF protein produced using CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purified from cell culture supernatant
Limitations	This product is for research use only
Protocol	ELISA 0.1 to 0.2 ug/ml; WB 0.5 to 2 ug/ml; IF 1 to 10 ug/ml Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
Purification	Protein G purification
References	-
Storage	Store at -20C to -70C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles
Uniprot ID	P55145

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/25/2025

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