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Mouse monoclonal antibody to HCV subtype 1b NS5B protein

Mouse monoclonal antibody to HCV subtype 1b NS5B protein

Item no.	ICO-A2-426-100
Manufacturer	Icosagen
Amount	100ug
Category	Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Monoclonal
Applications	ELISA, Western Blot
Clone	10D7
Specific against	other
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Background	Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.
Buffer	PBS pH 7.4, with 0.1% sodium azide
Clonality	Mouse monoclonal
Immunogen	HCV 1b NS5B
Immunogen Description	Recombinant Hepatitis C Virus subtype 1b nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)
Limitations	This product is for research use only TECHNICAL ASSISTANCE Please refer any technical questions to technical.supporticosagen.com
Protocol	WB in reduced conditions 1 ug/ml; Optimal conditions for IP should be determined for each particular application. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
Purification	Protein G purification
References	Nikonov A, Juronen E and Ustav M (2008). Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase. J. Biol Chem. 283(35):24089-102.
Storage	Store at - 20 …-70 C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result.
Uniprot ID	Q9WMX2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 10/23/2025

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