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Mouse monoclonal antibody to human laminin a5

Mouse monoclonal antibody to human laminin a5

Item no.	ICO-A2-610-100
Manufacturer	Icosagen
Amount	100ug
Category	Antibodies Cell Biology Immunohistochemistry Immunoprecipitation ELISA Cell Stainings ECM Primary Antibodies
Type	Antibody Monoclonal
Applications	ELISA, Immunohistochemistry, Immunoprecipitation
Clone	4B12
Specific against	other
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Background	Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cell-surface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their alpha chain, are expressed in a cell- and tissue-specific manner, and are differentially recognized by integrins
Buffer	PBS pH 7.4, with 0.1% sodium azide
Clonality	Mouse monoclonal
Immunogen	Human laminin a5
Immunogen Description	Laminin purified from human placenta (Chemicon)
Limitations	This product is for research use only
Protocol	ELISA 0.05 to 0.1 ug/ml; IP 0.5 mg/ml This antibody does not work in WB Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
Purification	Protein G purification
References	Wondimu Z, Geberhiwot T, Ingerpuu S, Juronen E, Xie X, Lindbom L, Doi M, Kortesmaa J, Thyboll J, Tryggvason K, Fadeel B, Patarroyo M. (2004) An endothelial laminin isoform, laminin-8 (alpha4beta1gamma1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis. Blood, 104(6):1859-66
Storage	Store at -20…-70C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles
Uniprot ID	-

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/25/2025

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