mouse anti-receptor-type tyrosine-protein phosphatase R isoforms antibody

blue ice

Molecular cell biology research

Antibody against receptor-type tyrosine-protein phosphatase R isoforms. Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72 kDa) is receptor-like, PTP-SL (60 kDa) is membrane associated and PTPPBS? (42 and 37 kDa) is a cytosolic phoaphatase. This antibody is directed to the common part of these proteins.