« Back
Home /
Anti-Human Caspase-8 Active Subunit (p18) - 0.2 mg

Anti-Human Caspase-8 Active Subunit (p18) - 0.2 mg

Item no.	LEIN-C1142-0.2mg
Manufacturer	Leinco Technologies
Amount	0.2 mg
Category	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	WB, ELISA
Clone	C81.349
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	ELISA Cap, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	Caspase-8 Active Subunit (p18)
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Caspase-8 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor–1 (TNFR-1) induced apoptosis. Activation of caspase 8 by proteolytic cleavage leads to the release of the active p18 and p10 subunits. These processed subunits associate to form an active enzyme.
Background	Caspase-8 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor–1 (TNFR-1) induced apoptosis. Activation of caspase 8 by proteolytic cleavage leads to the release of the active p18 and p10 subunits. These processed subunits associate to form an active enzyme.
PubMed	Caspase-8 Active Subunit (p18)
Manufacturer - Research Area	Apoptosis, Cell Biology, Immunology
Manufacturer - Specificity	Anti-Human Caspase-8 Active Subunit (p18) (clone C81.349) recognizes the human 18-20 kDa cleaved active subunit of caspase 8 and does not react with the inactive proenzyme. The antibody was developed using a synthetic peptide with residues mapping to the N-terminus of the (p18) subunit of human caspase 8.
RRID	AB_2828344
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

LEIN-C1142-0.2mg-safety-datasheet.pdf