Comparison

Anti-Human Cytokeratin 6/18 - Purified - 200 µg

Item no. LEIN-C161-200ug
Manufacturer Leinco Technologies
Amount 200 ug
Category
Type Antibody Monoclonal
Applications IHC
Clone LP34
Specific against Human (Homo sapiens)
Host Mouse
Citations 1. Moll, WR. et al. (1982) Cell 31:11
2. Gatter, KC. et al. (1982) J. Clin. Path. 35:125
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Applications
IHC FF, IHC FFPE
Manufacturer - Category
Cytokeratin|Primary Monoclonal Antibodies>Extracellular Matrix
Manufacturer - Targets
Cytokeratin 6/18
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
Anti-Human Cytokeratin 18, 6 (clone LP34) reacts with the cytokeratin polypeptides 18 and 6, with molecular weights of 45 kDa and 56 kDa, respectively. The antibody does not react with keratins 1, 8, or 19. Anti-Cytokeratin 18, 6 reacts in cryostat sections with epithelial tissues known to contain filamentous keratins. It reacts with single glandular epithelia to stratified squamous epithelia. Anti-Cytokeratin 18, 6 may be used in research studies to identify tumors as being of epithelial or mesothelial origin enabling aplastic carcinomas to be distinguished from other non-carcinoma types of tumors.1, 2 The antibody may also be used to trace areas of epithelial tissue in mixed tumors.
Background
Anti-Human Cytokeratin 18, 6 (clone LP34) reacts with the cytokeratin polypeptides 18 and 6, with molecular weights of 45 kDa and 56 kDa, respectively. The antibody does not react with keratins 1, 8, or 19. Anti-Cytokeratin 18, 6 reacts in cryostat sections with epithelial tissues known to contain filamentous keratins. It reacts with single glandular epithelia to stratified squamous epithelia. Anti-Cytokeratin 18, 6 may be used in research studies to identify tumors as being of epithelial or mesothelial origin enabling aplastic carcinomas to be distinguished from other non-carcinoma types of tumors.1, 2 The antibody may also be used to trace areas of epithelial tissue in mixed tumors.
PubMed
Cytokeratin 6/18
Manufacturer - Specificity
Mouse Anti-Human Cytokeratin 18, 6 (Clone LP34) recognizes Human Cytokeratin 18, 6. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2828671
Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen
UnKnown
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Cytokeratin 18, 6, LP34, KRT18, Human Cytokeratin, Anti-Human Cytokeratin 18, 6, Cytokeratin antibody, Clone LP34

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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