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Anti-Human CD49f (Integrin alpha6) (Clone 4F10) - Purified

Anti-Human CD49f (Integrin alpha6) (Clone 4F10) - Purified

Item no.	LEIN-C627-0.1mg
Manufacturer	Leinco Technologies
Amount	0.1 mg
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Flow Cytometry Immunoprecipitation Primary Antibodies
Type	Antibody Monoclonal
Applications	FC, IP
Clone	4F10
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Ramaswamy, A. et al. (1995) J. Path. 176(3):227 2. Dobson, H. et al. (1994) GUT 35:1343 3. Pignatelli, M. et al. (1992) Human Pathol. 23:1159
NCBI	3655
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Targets	CD4
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	For use within 1 month of purchase store at 2-8°C. For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
PubMed	CD49f
Ligand/Receptor	With integrin β1 (CD29) forms VLA-6, with integrin β4 (CD104) forms a6β4 integrin; laminin and kalinin are ligands for these receptors
Manufacturer - Specificity	Mouse Anti-Human CD49f (Clone 4F10) recognizes Human CD49f. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody is specific to the integrin alpha6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha6 chain, which consists of a single disulphide linked 120 kDa subunit and a small doublet subunit of 25/30 kDa, is non-covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha6/beta1 complex or with integrin beta4 chain (alpha6/beta4) The antigen is also expressed on platelets, monocytes, thymocytes and T-lymphocytes.
RRID	AB_2829785
Concentration	0.1 mg/ml
Formulation	This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Immunogen	Cell Line SW/222 (Human Colorectal Carcinoma)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-C627-0.1mg-safety-datasheet.pdf