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Anti-Human FSH - HRP - 1.0 ml

Anti-Human FSH - HRP - 1.0 ml

Item no.	LEIN-H101-1.0ml
Manufacturer	Leinco Technologies
Amount	1 ml
Category	Antibodies ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	ELISA
Clone	181
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Ryu KZ et al. (2000) J Korean Soc Endocrinol. 15: 179 2. Sluss Patrick et al. (2002) J clin endocrin and metabolism 87: 3702
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	ELISA Det
Manufacturer - Category	Primary Monoclonal Antibodies>Endocrinology Hormones
Manufacturer - Targets	FSH
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Product Description	Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone. The synthesis of beta subunit is the primary rate-limiting step in the synthesis of each hormone.1 Human mutations in the FSH beta gene have been shown to produce complete deficiency states in which pubertal development and reproductive capacity are inhibited.2
Background	Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone. The synthesis of beta subunit is the primary rate-limiting step in the synthesis of each hormone.¹ Human mutations in the FSH beta gene have been shown to produce complete deficiency states in which pubertal development and reproductive capacity are inhibited.²
Cross Reactivity	Paired with Leinco Prod. No. F103, Clone No. 176: FSH 100%, BhCG < 1%, LH < 4%, ihCG, TSH < 1% 3, 000 mlU/ml hCG causes 4.5% decrease in observed FSH. At higher concentrations of hCG, observed FSH reduced to zero. Paired with Leinco Prod. No. C102, Clone No. 151: FSH 100%, BhCG < 1%, ihCG , FSH < 1%, TSH < 1%. At high concentrations of hCG, observed FSH reduced to zero.
PubMed	Follicle Stimulating Hormone Beta
Manufacturer - Research Area	Hormones, IVD Raw Material
Manufacturer - Specificity	Mouse Anti-Human Follicle Stimulating Hormone β (Clone 181) recognizes Human Follicle Stimulating Hormone β. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830303
Concentration	0.5 mg/ml
Formulation	This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Immunogen	Purified Recombinant Human Follicle Stimulating Hormone Beta (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Follicle Stimulating Hormone Beta, 181, FSH-β, Human, Anti-Human Follicle Stimulating Hormone Beta-Horseradish Peroxidase

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-H101-1.0ml-safety-datasheet.pdf