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Anti-Human HB-EGF – Biotin - 50 µg

Anti-Human HB-EGF – Biotin - 50 µg

Item no.	LEIN-H1489-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Higashiyama, S. et al. (1993) Journal of Cell Biology 122: 933 2. Higashiyama, S. et al. (2004) Cytokine Growth Factor Rev. 15: 13 3. Miyamoto, S. et al. (2008) Mol Cancer Ther. 7: 3441
NCBI	1839
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Det, WB
Manufacturer - Category	Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets	HB-EGF
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted bioin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Heparin-binding EGF-like growth factor (HB-EGF) is a monomeric heparin binding O-glycosylated protein1 and a member of the EGF family of proteins. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function.2 HB-EGF contributes to cell adhesion, invasion, and angiogenesis, which are integral to transcoelomic metastasis in ovarian cancer.3
Background	Heparin-binding EGF-like growth factor (HB-EGF) is a monomeric heparin binding O-glycosylated protein¹ and a member of the EGF family of proteins. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function.² HB-EGF contributes to cell adhesion, invasion, and angiogenesis, which are integral to transcoelomic metastasis in ovarian cancer.³
PubMed	HB-EGF
Manufacturer - Specificity	Goat Anti-Human Heparin-Binding EGF-Like Growth Factor (HB-EGF) recognizes Human HB-EGF. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830325
Formulation	This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen	Purified Recombinant Human HB-EGF (Accession # Q99075)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Heparin-Binding EGF-Like Growth Factor, DTR, DTS, DTSF, HEGFL, HB-EGF, Human HB-EGF, Anti-Human HB-EGF-Biotin, HB EGF, Human HB EGF, diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor), Dtr, DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor), Dts, DTSF, HBEGF, HB-EGF, Hegfl, heparin-binding EGF-like growth factor, heparin-binding epidermal growth factor, proheparin-binding EGF-like growth factor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-H1489-50ug-safety-datasheet.pdf