Anti-Human IL-4 - PE - 50 µg

Quality Tested by Leinco Flow Cytometry:For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume.

IL-4

Next Day 2 - 8°C

IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.

IL-4

Cell Biology, Immunology, Neuroinflammation, Neuroscience, Other Molecules

AB_2830507

This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

Purified Recombinant Human IL-4 (> 98%)

Monoclonal Antibody, Interleukin-4, BCGF, BCDF, B Cell Stimulating Factor, BSF-1, MP4-25D2, IL-4, Human, Anti-Human IL-4 - R-PE