Comparison

Anti-Mouse ICOS (Clone C398.4A) - Purified (PhenoCyler-Fusion (CODEX)® Ready) - 50 µg

Item no. LEIN-I-2012-50ug
Manufacturer Leinco Technologies
Amount 50 ug
Category
Type Antibody Monoclonal
Applications IHC
Clone C398.4A
Specific against other
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Manufacturer - Applications
IHC FF, PhenoCycler®
Manufacturer - Category
Primary Monoclonal Antibodies>Immune Checkpoints|PhenoCycler®>PhenoCycler® Validated Antibodies|Primary Monoclonal Antibodies>SurfaceTag Human CD Markers
Manufacturer - Targets
ICOS
Storage Conditions
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Antigen Distribution
ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages.
Protein
ICOS
Keywords
Anti-Mouse ICOS, BX034, Clone C398.4A, Alexa 488, RX034

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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