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Anti-Human IL-17E - Biotin - 50 µg

Anti-Human IL-17E - Biotin - 50 µg

Item no.	LEIN-I-411-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Gurney, AL. et al. (2001) J Biol Chem. 276:1660 2. Gurney, AL. et al. (2001) J Immunol. 167:6559 3. Hamid, Q. et al. (2006) J Allergy Clin. Immunol. 117:590
NCBI	64806
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Quality Tested by Leinco Western Blotting: To detect Human IL-17E this biotin conjugate can be used at a concentration of 0.1 µg/ml. This biotin conjugate should be used in conjunction with compatible second-step reagents such as PN:A106 and a chromogenic substrate such as PN:T343. The detection limit for Human IL-17E is 1.5-3.0 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:I-199.
Manufacturer - Category	Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets	IL-17E
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Interleukin (IL)-17E, is a novel member of the IL-17 family of cytokines1 and a unique pleiotropic cytokine and may be an important mediator of inflammatory and immune responses.2 IL17B is also a ligand for the cytokine receptor IL17BR. IL-17E induces activation of NF-kappaB and stimulates production of the proinflammatory chemokine IL-8. 1 IL-17E may contribute to the induction and maintenance of eosinophilic inflammation in the airways by acting on lung fibroblasts and therefore has a role in asthma pathophysiology.3
Background	Interleukin (IL)-17E, is a novel member of the IL-17 family of cytokines¹ and a unique pleiotropic cytokine and may be an important mediator of inflammatory and immune responses.² IL17B is also a ligand for the cytokine receptor IL17BR. IL-17E induces activation of NF-kappaB and stimulates production of the proinflammatory chemokine IL-8. ¹ IL-17E may contribute to the induction and maintenance of eosinophilic inflammation in the airways by acting on lung fibroblasts and therefore has a role in asthma pathophysiology.³
PubMed	IL-17E
Manufacturer - Specificity	Goat Anti-Human Interleukin-17E (IL-17E) recognizes Human IL-17E. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830673
Formulation	This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen	Purified Recombinant Human IL-17E (Accession # Q9H293)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Interleukin-17E, IL25, IL-17E, Human IL-17E, Anti-Human IL-17E-Biotin, Human IL17E, IL17E, IL17E, IL-17E, IL17Einterleukin-17E, IL25, IL-25, interleukin 17E, interleukin 25, Interleukin-17E, interleukin-25

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-I-411-50ug-safety-datasheet.pdf