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Anti-Human MIP-4 - Biotin - 50 µg

Anti-Human MIP-4 - Biotin - 50 µg

Item no.	LEIN-M199-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Category	Antibodies Flow Cytometry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, FC, ELISA
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Nomiyama, H. et al. (1997) J. Biol. Chem. 272: 5846 2. Kucharzik, T. et al. (2005) J. Pathol. 166: 1647
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA Det, FC, WB
Manufacturer - Category	Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets	MIP-4
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Macrophage Inflammatory Protein-4 (MIP-4) produced in E.Coli is a single, non-glycosylated polypeptide that attracts lymphocytes but not monocytes or granulocytes and is involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses. MIP-4 is expressed at high levels in lung, lymph nodes, placenta, and bone marrow, not expressed by peripheral blood monocytes, and a monocyte-to-macrophage differentiation is a prerequisite for expression.
Background	Macrophage Inflammatory Protein-4 (MIP-4) produced in E.Coli is a single, non-glycosylated polypeptide that attracts lymphocytes but not monocytes or granulocytes and is involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses. MIP-4 is expressed at high levels in lung, lymph nodes, placenta, and bone marrow, not expressed by peripheral blood monocytes, and a monocyte-to-macrophage differentiation is a prerequisite for expression.
PubMed	MIP-4
Manufacturer - Specificity	Goat Anti-Human Macrophage Inflammatory Protein-4 (MIP-4) recognizes Human MIP-4. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2831376
Formulation	This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen	Purified Recombinant Human MIP-4 (Accession # P55774)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, MIP-4, Pulmonary and Activation-Regulated Chemokine (PARC), SCYA18, DC-CK1, AMAC-1, DCCK1, CKb7, CCL18, MIP-4, Human, Anti-Human MIP-4-Biotin, Human MIP4, MIP4, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1CC chemokine ligand 18, AMAC-1Small-inducible cytokine A18, CCL18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), CKb7, DC-CK1, DC-CK1CC chemokine PARC, DCCK1Macrophage inflammatory protein 4, Dendritic cell chemokine 1, MIP4, MIP-4, MIP-4C-C motif chemokine 18, PARC, PARCPulmonary and activation-regulated chemokine, SCYA18chemokine (C-C), dendritic, small inducible cytokine A18, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-M199-50ug-safety-datasheet.pdf