Anti-Mouse γ/δ (TCR) [Clone UC7-13D5] — Purified - 500 µg

γ/δ T-Cell Receptor

Next Day Ambient

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

γ/δ T-Cell Receptor

The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.

0.5 mg/ml

γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.