Comparison

Anti-Mouse Vγ2 TCR - Purified - 0.5 mg

Item no. LEIN-T210-0.5mg
Manufacturer Leinco Technologies
Amount 0.5 mg
Category
Type Antibody Monoclonal
Applications FC, IP
Clone UC3-10A6
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Armenian
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Category
Mouse T-Cell Receptor Complex|Primary Monoclonal Antibodies
Manufacturer - Targets
Vγ 2 T-Cell Receptor
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Function
Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens.
PubMed
Vγ 2 T-Cell Receptor
Manufacturer - Research Area
Adaptive Immunity, Immunology
Manufacturer - Specificity
This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes.
RRID
AB_2892973
Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Immunogen
Purified Recombinant Mouse TCR (> 98%)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Vγ 2 T-Cell Receptor , Vγ 4, UC3-10A6, TCR, Mouse, Anti-Mouse Vγ 2 T-Cell Receptor (TCR)-Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.5 mg
Available: In stock
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