Anti-Mouse TCR β chain (TCR) - Purified (PhenoCyler-Fusion (CODEX)® Ready) - 50 µg

Mouse T-Cell Receptor Complex|PhenoCycler®>PhenoCycler® Validated Antibodies

Next Day Ambient

TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells1. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond2. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling3, 4. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival5, 6.

This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.

Monoclonal Antibody, TCR beta, H57-597, TCR β, Mouse, Anti-Mouse β (TCR) - Purified, Costimulation, Depletion, TCR