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p53 [DO-7]

p53 [DO-7]

Item no.	MEDY-MC0219
Manufacturer	Medaysis
Amount	1 ml
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IP, IHC, ICC
Clone	DO-7
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian), Cow (Bos taurus)
Host	Mouse
Isotype	IgG2b
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	IgG2b/κ
Cellular Localization	nucleus
Description	p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair. p53 is overexpressed in over 50% of human cancers. Positive staining of p53 detected by immunohistochemistry has been observed in colon cancer, breast cancer, lung cancer, prostate cancer and ovary cancer.
Intended Use	RUO
Positive Control	breast ca, colon ca
Biomarker Panel	Breast Pathology
IHC Dilution	50-200

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 ml

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Delivery expected until 9/18/2025

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