Rabbit antibody to NMDAR1

FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction a€C synapse a€C postsynaptic cell membrane; Multi-pass membrane protein.

IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

12 months after reconstitution

1. Yamazaki M, et al. FEBS Lett. 300:39-45(1992)

A synthetic peptide from extracellular domain of mouse NMDAR1 conjugated to blue carrier protein was used as the antigen.

http://www.uniprot.org/uniprot/Q05586
http://www.uniprot.org/uniprot/P35439
http://www.uniprot.org/uniprot/P35438

Polyclonal

Lyophilised