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Rabbit antibody to SHANK3

Rabbit antibody to SHANK3

Item no.	OSS00115W
Manufacturer	Osenses
Amount	100ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SH3 and multiple ankyrin repeat domains protein 3, ProSAP2, Proline rich synapse associated protein 2, PSAP2
Similar products	PSAP2, Proline rich synapse associated protein 2, ProSAP2, SH3 and multiple ankyrin repeat domains protein 3
Available
Also known	SH3 and multiple ankyrin repeat domains protein 3, ProSAP2, Proline rich synapse associated protein 2, PSAP2
Target	Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. Subcellular location: Cytoplasm. Cell junction a€C synapse. Cell junction a€C synapse a€C postsynaptic cell membrane a€C postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD. Tissue specificity: Widely expressed in brain.
Spcs X-react.	Human, rat, mouse. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Dunham I, et al. ature 402:489-495(1999)
Limitation	For research use only
Immunogen	A synthetic peptide from human SHANK3 conjugated to blue carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/Q9BYB0 http://www.uniprot.org/uniprot/Q9JLU4 http://www.uniprot.org/uniprot/Q4ACU6
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for SHANK3.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 12/18/2025

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