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Natalizumab (ITGA4/CD49d) Antibody, Monoclonal

Natalizumab (ITGA4/CD49d) Antibody, Monoclonal

Item no.	PRS-10-090-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Neuroscience Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Primary Antibodies
Type	Antibody Monoclonal
Specific against	other
Isotype	IgG4 Kappa
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AN 100226,BG00002, ITGA4/CD49d, ITGA4/CD49d
Available
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at -80°C
Manufacturer - Research Area	Drug Analogues
Background	Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1).Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.
Purification	>95%
Buffer	PBS buffer pH7.5
Immunogen	Humanized / ITGA4/CD49d [Homo sapiens]
Clonality	Monoclonal
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/4/2025

Express Delivery: Save 27 days

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