SARS-CoV-2 RBD Potent Neutralizing Antibody, monoclonal, Chimeric

Human IgG1/kappa

For long term storage, the product should be stored at lyophilized state at -20°C or lower..Please avoid repeated freeze-thaw cycles.This product is stable after storage at:.-20 to -70°C for 12 months in lyophilized state from date of receipt; .-70°C for 3 months under sterile conditions after reconstitution.

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Batch dependent

Anti-SARS-CoV-2 RBD Potent Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM128) is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein.

Surface glycoprotein

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.