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MDM2 Antibody

MDM2 Antibody

Item no.	PRS-14-921-50uL
Manufacturer	ProSci
Amount	50 uL
Quantity options	100 uL
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Sarcoma Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	MDM2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MDM2, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse), HGNC:6973, MGC71221, hdm2, mouse double minute 2 homolog, mouse double minute 2, human homolog of, p53-binding protein, p53-binding protein MDM2, ubiquitin-protein ligase E3 Mdm2, HDMX, ACTFS
Available
Manufacturer - Applications	WB: 1:500 - 1:2000
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 52kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Background	This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Purification	Affinity purification
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 200-430 of human MDM2 (NP_002383.2).
Clonality	Polyclonal
NCBI Official Name	MDM2 oncogene, E3 ubiquitin protein ligase
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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