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SMPD1 Antibody

SMPD1 Antibody

Item no.	PRS-25-269-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot ELISA Enzymes Fatty Acid Catabolism Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Zeidan, Y.H., (2008) J. Cell Biol. 181 (2), 335-350.
NCBI	SMPD1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SMPD1,ASM,NPD,ASMASE
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMPD1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	65 kDa
Manufacturer - Research Area	Membrane , Cancer , Signal Transduction , Neuroscience
Background	SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB).
By Type	Membrane, Cancer, Signal Transduction, Neuroscience
Modifications	None
Protein Gi #	56117840
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	SMPD1 antibody can be used for detection of SMPD1 by ELISA at 1:62500. SMPD1 antibody can be used for detection of SMPD1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMPD1.
Clonality	Polyclonal
NCBI Official Name	sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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