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NR1H3 Antibody

NR1H3 Antibody

Item no.	PRS-25-443-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot ELISA Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Torra, I.P., (2008) Mol. Cell. Biol. 28 (8), 2626-2636.
NCBI	NR1H3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NR1H3,LXR-a,LXRA,RLD-1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR1H3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	50 kDa
Manufacturer - Research Area	Transcription , Cancer , Signal Transduction
Background	Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
By Type	Transcription, Cancer, Signal Transduction
Modifications	None
Protein Gi #	194294517
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	PRS-1219-0.1mg
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	NR1H3 antibody can be used for detection of NR1H3 by ELISA at 1:62500. NR1H3 antibody can be used for detection of NR1H3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1H3.
Clonality	Polyclonal
NCBI Official Name	nuclear receptor subfamily 1, group H, member 3
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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