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UTX Antibody

UTX Antibody

Item no.	PRS-25-522-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Hong, S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444.
NCBI	KDM6A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	UTX,DKFZp686A03225,MGC141941,bA386N14.2,UTX,KABUK2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UTX antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	154 kDa
Manufacturer - Research Area	Transcription
Background	UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
By Type	Transcription
Modifications	None
Protein Gi #	189011544
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	PRS-1219-0.1mg
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	UTX antibody can be used for detection of UTX by ELISA at 1:312500. UTX antibody can be used for detection of UTX by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UTX.
Clonality	Polyclonal
NCBI Official Name	lysine (K)-specific demethylase 6A
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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