Comparison

FZD4 Antibody

Item no. PRS-25-683-100ul
Manufacturer ProSci
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Conjugate/Tag Unconjugated
Citations Dufourcq, P., (2008) Am. J. Pathol. 172 (1), 37-49.
NCBI FZD4
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FZD4,EVR1,FEVR,FZD4S,Fz-4,FzE4,GPCR,MGC34390,Fz4,hFz4,CD344
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FZD4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight
60 kDa
Manufacturer - Research Area
Membrane , Cancer , Signal Transduction
Background
FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
By Type
Membrane, Cancer, Signal Transduction
Modifications
None
Protein Gi #
22547161
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control 1
Concentration
batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note
FZD4 antibody can be used for detection of FZD4 by ELISA at 1:312500. FZD4 antibody can be used for detection of FZD4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FZD4.
Clonality
Polyclonal
NCBI Official Name
frizzled class receptor 4
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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