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HERC5 Antibody

HERC5 Antibody

Item no.	PRS-25-833-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Salon, C., (2007) Oncogene 26 (48), 6927-6936.
NCBI	HERC5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HERC5, CEB1, CEBP1
Available
Manufacturer - Applications	HERC5 antibody can be used for detection of HERC5 by ELISA at 1:312500. HERC5 antibody can be used for detection of HERC5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Shipping Temperature	blue ice or room temperature
Storage Conditions	For short periods of storage (days) store at 4°C. For longer periods of storage, store HERC5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	117 kDa
Manufacturer - Research Area	Cell Cycle
Background	HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Protein Gi #	110825982
Purification	Antibody is purified by peptide affinity chromatography method.
Concentration	Batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HERC5.
Clonality	Polyclonal
NCBI Official Name	HECT and RLD domain containing E3 ubiquitin protein ligase 5
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 9/4/2025

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