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AKT1S1 Antibody

AKT1S1 Antibody

Item no.	PRS-26-278-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Antibodies Cell Biology Cell Status Western Blot ELISA Autophagy Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Fonseca, B.D., (2008) Biochem. J. 411 (1), 141-149.
NCBI	AKT1S1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AKT1S1,Lobe,MGC2865,PRAS40
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AKT1S1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	27 kDa
Background	AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
By Type	Other
Modifications	None
Protein Gi #	400153980
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	293T Cell Lysate
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	AKT1S1 antibody can be used for detection of AKT1S1 by ELISA at 1:62500. AKT1S1 antibody can be used for detection of AKT1S1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AKT1S1.
Clonality	Polyclonal
NCBI Official Name	AKT1 substrate 1 (proline-rich)
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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