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NKIRAS1 Antibody

NKIRAS1 Antibody

Item no.	PRS-27-004-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cytoskeleton Western Blot ELISA Primary Antibodies small GTPases Ras Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Adams, M.D., (er) Ann. Rheum. Dis. (2008) In press.
NCBI	NKIRAS1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NKIRAS1,KBRAS1,kappaB-Ras1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NKIRAS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	22 kDa
Manufacturer - Research Area	Signal Transduction , Immunology
Background	NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
By Type	Signal Transduction, Immunology
Modifications	None
Protein Gi #	9966809
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	PRS-1205-0.1mg
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	NKIRAS1 antibody can be used for detection of NKIRAS1 by ELISA at 1:62500. NKIRAS1 antibody can be used for detection of NKIRAS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NKIRAS1.
Clonality	Polyclonal
NCBI Official Name	NFKB inhibitor interacting Ras-like 1
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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