PAX6 Antibody

Blue Ice

48 kDa

PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.

None

Antibody is purified by peptide affinity chromatography method.

batch dependent

PAX6 antibody can be used for detection of PAX6 by ELISA at 1:62500. PAX6 antibody can be used for detection of PAX6 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.