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PHB Antibody

PHB Antibody

Item no.	PRS-27-716-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Fraering, P.C., et al., (2004) Biochemistry 43 (30), 9774-9789.
NCBI	PHB
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PHB, PHB1, HEL-215, HEL-S-54e
Available
Manufacturer - Applications	PHB antibody can be used for detection of PHB by ELISA at 1:1562500. PHB antibody can be used for detection of PHB by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Shipping Temperature	blue ice or room temperature
Storage Conditions	For short periods of storage (days) store at 4°C. For longer periods of storage, store PHB antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	30 kDa
Manufacturer - Research Area	Transcription , Cell Cycle , Cancer
Background	Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Protein Gi #	4505773
Purification	Antibody is purified by peptide affinity chromatography method.
Positive Control 1	PRS-1205-0.1mg
Concentration	Batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHB.
Clonality	Polyclonal
NCBI Official Name	prohibitin
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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