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P2RX1 Antibody

P2RX1 Antibody

Item no.	PRS-28-242-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Dog (Canine, Canis lupus familiaris)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Vial, C., (2006) Biochem. Biophys. Res. Commun. 343 (2), 415-419.
NCBI	P2RX1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	P2RX1, P2X1
Available
Manufacturer - Applications	P2RX1 antibody can be used for detection of P2RX1 by ELISA at 1:312500. P2RX1 antibody can be used for detection of P2RX1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Shipping Temperature	blue ice or room temperature
Storage Conditions	For short periods of storage (days) store at 4°C. For longer periods of storage, store P2RX1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	45 kDa
Manufacturer - Research Area	Membrane , Cancer , Signal Transduction , Apoptosis
Background	P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Protein Gi #	4505545
Purification	Antibody is purified by protein A chromatography method.
Concentration	Batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX1.
Clonality	Polyclonal
NCBI Official Name	purinergic receptor P2X, ligand-gated ion channel, 1
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 9/4/2025

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