MUC1 Antibody

Blue Ice

22 kDa, 28 kDa, 28 kDa, 16 kDa, 17 kDa, 30 kDa

MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

None

Antibody is purified by peptide affinity chromatography method.

batch dependent

MUC1 antibody can be used for detection of MUC1 by ELISA at 1:312500. MUC1 antibody can be used for detection of MUC1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.