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NR3C2 Antibody

NR3C2 Antibody

Item no.	PRS-30-075-100ul
Manufacturer	ProSci
Amount	100 ul
Category	Antibodies Immunohistochemistry Western Blot ELISA Cardiovascular Research Heart Failure Hypertension Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296.
NCBI	NR3C2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NR3C2,MCR,MGC133092,MLR,MR,NR3C2VIT
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR3C2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight	107 kDa
Manufacturer - Research Area	Transcription , Cancer , Signal Transduction
Background	NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
By Type	Transcription, Cancer, Signal Transduction
Modifications	None
Protein Gi #	158508572
Purification	Antibody is purified by protein A chromatography method.
Positive Control 1	A172 Cell Lysate
Concentration	batch dependent
Buffer	Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note	NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2.
Clonality	Polyclonal
NCBI Official Name	nuclear receptor subfamily 3, group C, member 2
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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