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LSD1AOF2 Antibody [1B2F2 / 1B2E5]

LSD1AOF2 Antibody [1B2F2 / 1B2E5]

Item no.	PRS-32-188-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Neural Epigenetics Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC, ELISA
Clone	1B2F2 / 1B2E5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64. Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9.
NCBI	KDM1A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AOF2,KDM1,KIAA0601,LSD1,BRAF35-HDAC complex protein BHC110AOF2,BHC110
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	LSD1/AOF2 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Background	The amine oxidase domain 2（AOF2）gene encodes a nuclear protein(LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
By Type	Other
Modifications	None
Protein Gi #	51315808
Concentration	batch dependent
Buffer	Ascitic fluid containing 0.03% sodium azide.
Application Note	Western Blot:1:500 - 1:2, 000 IHC(P):1:500 - 1:2, 000 IHC(F):1:500 - 1:2, 000 ELISA:Propose dilution 1:10, 000. Determining optimal working dilutions by titration test.
Immunogen	Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3).
Clonality	Monoclonal
NCBI Official Name	lysine (K)-specific demethylase 1A
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/4/2025

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