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BACE1 Antibody [3C1C3]

BACE1 Antibody [3C1C3]

Item no.	PRS-32-238-0.1mL
Manufacturer	ProSci
Amount	0.1 mL
Category	Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Flow Cytometry Western Blot ELISA Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, FC, ICC, ELISA
Clone	3C1C3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	J Neurochem. 2012 Jan;120 Suppl 1:62-70. Eur J Neurosci. 2010 Oct;32(7):1223-38.
NCBI	BACE1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BACE Antibody: ASP2,BACE,HSPC104,KIAA1149,Beta-secretase 1,Aspartyl protease 2,ASP2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	BACE monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area	Neuroscience
Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
By Type	Neuroscience
Modifications	None
Concentration	batch dependent
Buffer	Purified antibody in PBS with 0.05% sodium azide.
Application Note	ELISA: 1/10000 Western Blot: 1/500 - 1/2000 ICC: 1/200 - 1/1000 Flow Cytometry: 1/200 - 1/400
Immunogen	Rurified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
Clonality	Monoclonal
NCBI Official Name	beta-secretase 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mL

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Delivery expected until 12/4/2025

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