« Back
Home /
SIN1 Antibody

SIN1 Antibody

Item no.	PRS-33-014-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	MAPKAP1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	MAPKAP1 Antibody: MIP1,SIN1,JC310,SIN1b,SIN1g,MIP1,Target of rapamycin complex 2 subunit MAPKAP1,Mitogen-activated protein kinase 2-associated protein 1,TORC2 subunit MAPKAP1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Signal Transduction
Background	mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
By Type	Signal Transduction
Modifications	None
Purification	Protein A purified antibody
Concentration	0.5 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Western blot: 1-3 ug/ml Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
Immunogen	A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
Clonality	Polyclonal
NCBI Official Name	mitogen-activated protein kinase associated protein 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 12/4/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer