CLEC1 Antibody

Primary Antibodies

Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

None

0.5 mg/mL

Western blot: 2-5 ug/ml
Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher