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NKIRAS1 Antibody [NRAS285]

NKIRAS1 Antibody [NRAS285]

Item no.	PRS-33-038-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Ras Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Clone	NRAS285
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
NCBI	NKIRAS1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	KappaB ras Antibody: KBRAS1,kappaB-Ras1,KBRAS1,NF-kappa-B inhibitor-interacting Ras-like protein 1,I-kappa-B-interacting Ras-like protein 1,Kappa B-Ras protein 1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Signal Transduction
Background	NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions. NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
By Type	Signal Transduction
Modifications	None
Purification	Protein G purified antibody
Concentration	0.5 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Western blot: 5-10 ug/ml Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
Immunogen	A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Clonality	Monoclonal
NCBI Official Name	NFKB inhibitor interacting Ras-like 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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