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KRT8 Antibody [K8.8]

KRT8 Antibody [K8.8]

Item no.	PRS-33-166-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Bladder Cancer Oligodendrocyte Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF, IHC
Clone	K8.8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
NCBI	KRT8
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	KRT8,CARD2,CK8,CYK8,K2C8,K8,KO,CK-8
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer
Background	KRT8, also called Cytokeratin 8, is a low molecular weight keratin of approximately 50 kDa. It participates in cellular differentiation and signal transduction, protects against apoptosis, stress and injury, and helps maintain cellular structural integrity. KRT8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas.
By Type	Cancer
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Western blot: 0.5-1 ug/ml Flow Cytometry: 0.5-1 ug/million cells IF: 1-2 ug/ml IHC (FFPE): 0.5-1.0 ug/ml for 30 min at RT (1) Prediluted format : incubate for 30 min at RT (2) Differences in protocols and secondaries may require the KRT8 antibody to be titered for optimal performance. 1. FFPE staining requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Manufacturer - Specificity	Does not react with rat
Immunogen	Human carcinoma keratin was used as the immunogen for this KRT8 antibody.
Clonality	Monoclonal
NCBI Official Name	keratin 8
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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