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MUC18 Antibody [OJ79c]

MUC18 Antibody [OJ79c]

Item no.	PRS-33-174-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Antibodies Flow Cytometry Immunofluorescence Primary Antibodies By Organ Bladder Cancer Adhesion Molecule Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, IF
Clone	OJ79c
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
NCBI	MCAM
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cell surface glycoprotein MUC18,Cell surface glycoprotein P1H12,Melanoma cell adhesion molecule,Melanoma-associated antigen A32,Melanoma-associated antigen MUC18,S-endo 1 endothelial-associated antigen,CD146,MCAM,MUC18
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Immunology, Signal Transduction
Background	The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MUC18 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MUC18 / CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
By Type	Cancer, Immunology, Signal Transduction
Modifications	None
Purification	Protein G purified antibody
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Flow Cytometry: 0.5-1 ug/million cells IF: 0.5-1.0 ug/ml The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the MUC18 antibody to be titered up or down for optimal performance.
Immunogen	Recombinant human protein was used as the immunogen for this MUC18 antibody.
Clonality	Monoclonal
NCBI Official Name	melanoma cell adhesion molecule
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/6/2025

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